LactiGo vs. Biofreeze: A Comprehensive Comparison

Quick answer: LactiGo is the better premium choice for an athlete who values a differentiated topical formula built around menthol, L-carnosine, magnesium sulfate, an active U.S. patent covering a carnosine-magnesium complex, and Informed-Sport certification. Biofreeze is the better conventional choice for someone prioritizing a stronger menthol cooling sensation, broad retail availability, lower typical cost, or multiple application formats. Both products are menthol topical analgesics, and no direct LactiGo-versus-Biofreeze clinical trial proves that one finished product provides better pain relief.[1–9]

That answer is more useful than declaring one universal winner.

LactiGo and Biofreeze overlap in one important way: their current U.S. labels support temporary relief of minor muscle and joint aches. But the formulas, positioning, evidence, certification, formats, and value proposition are different. Biofreeze is primarily a menthol pain-relief brand. LactiGo is positioned as a premium athlete-focused topical gel whose current Drug Facts label identifies menthol as the active analgesic ingredient while listing L-carnosine and magnesium sulfate as inactive ingredients.[1,2]

The central question is therefore not simply, "Which one feels colder?" It is, "What are you paying for, what does the label support, and which product better matches your goal?" If you are deciding between routes rather than brands, remember that topical muscle rubs and oral supplements serve different goals.

Bottom line: Choose LactiGo when you want the more specialized athlete-focused formula and value its patented carnosine-magnesium formulation strategy plus Informed-Sport certification. Choose Biofreeze when you mainly want conventional menthol cooling relief, more applicator options, and easier retail access. Do not treat either gel as proof that an injury has healed or that training through pain is safe.

Table of Contents

• The short answer
• What exactly is being compared?
• LactiGo vs. Biofreeze at a glance
• Menthol strength and pain-relief claims
• What makes LactiGo a premium formula?
• What the patent does—and does not—prove
• What the human evidence shows
• Feel, formats, availability, and value
• Which product should you choose?
• Safety and responsible use
• Final verdict

Is LactiGo Better Than Biofreeze? The Short Answer

For a performance-minded buyer, LactiGo is the more distinctive premium option. It combines label-supported menthol analgesia with an athlete-centered formulation that includes L-carnosine and magnesium sulfate, is associated with an active U.S. patent covering a topical carnosine-magnesium complex, and is listed by Informed-Sport as a certified brand.[1,3,4,7]

For a shopper who wants a straightforward cooling analgesic, Biofreeze is the more conventional option. The standard green and colorless Biofreeze gels compared in this article list menthol 4% as the active ingredient, are available in familiar retail channels, and sit within a much larger product range that includes gels, roll-ons, sprays, patches, creams, and sticks.[2,8,9]

Neither conclusion proves that one product relieves every person's pain better. There is no published head-to-head randomized trial of LactiGo versus Biofreeze. The two products also have not been shown to be dose-equivalent simply because one contains 1.25% menthol and the other contains 4%.

Best evidence-based answer: LactiGo is "better" when better means a more specialized formula, athlete-oriented quality assurance, and a carnosine-magnesium technology story. Biofreeze is "better" when better means a conventional higher-menthol product, many formats, broad access, or lower cost. For pain-relief effectiveness, individual response and the complete formulation matter, and the direct comparison has not been tested.

What Exactly Is Being Compared?

Biofreeze is a product family, not one formula. Different Biofreeze products can have different menthol concentrations, inactive ingredients, age directions, and application systems. This article compares LactiGo with Menthol Performance & Recovery Gel with the standard U.S. Biofreeze Pain Relief Gel in the green or colorless 3-fluid-ounce tube—the closest common gel-to-gel comparison.[1,2,8]

LactiGo's current DailyMed label lists:

• Active ingredient: menthol 1.25%
• Purpose: topical analgesic
• Use: temporary relief of minor aches and pains of muscles and joints
• Inactive ingredients: ethoxydiglycol, glycerine, L-carnosine, magnesium sulfate, phenoxyethanol, water, and xanthan gum[1]

The current U.S. Drug Facts for the standard Biofreeze gel lists:

• Active ingredient: menthol USP 4%
• Purpose: pain-relieving gel
• Uses: temporary relief of minor muscle and joint aches associated with simple backache, arthritis, strains, bruises, and sprains
• Inactive ingredients: a formula that includes aloe, burdock, arnica, Boswellia, calendula, green tea, camphor, glycerin, isopropyl alcohol, silica, water, and other ingredients; the green version also contains color additives[2,8]

The inactive lists matter for preference, tolerability, texture, and differentiation. They do not mean every inactive ingredient has independently proven clinical effects in the finished OTC product.

LactiGo vs. Biofreeze at a Glance

Important comparison rule: The menthol percentage, number of ingredients, patent status, price, and cooling intensity cannot individually establish that one complete product relieves pain better. A finished formulation must be tested against the other product to support that claim.

Menthol Strength: Does Biofreeze's 4% Mean It Works Better?

No. Biofreeze's standard gel contains more menthol by percentage than LactiGo—4% versus 1.25%—but "more menthol" is not the same claim as "better finished product."[1,2]

What menthol contributes

Apply only as directed to intact skin. A cooling sensation may change how an area feels without proving that an injury has healed.

Menthol activates cold-sensitive signaling that includes the TRPM8 receptor. That can create a cooling sensation and alter pain perception without proving that the underlying muscle temperature has dropped or that tissue repair has accelerated.[12]

Both labels rely on menthol for their OTC analgesic purpose. In LactiGo, L-carnosine and magnesium sulfate appear on the inactive-ingredient list. In the standard Biofreeze gel, menthol is likewise the active pain-relieving ingredient while the botanical extracts and other formula components are inactive.[1,2]

Why a higher percentage is not a simple score

Perceived intensity depends on more than the percentage printed on the label. The vehicle, amount applied, skin area, evaporation, other ingredients, individual sensitivity, and condition of the skin can all affect how a topical feels. Menthol can also produce irritation or burning at higher exposures in some circumstances.[12]

No reliable head-to-head dose-response study was found showing that Biofreeze's 4% standard gel provides more effective or longer relief than LactiGo's 1.25% formula. It is fair to predict a potentially stronger cooling sensation from the higher-menthol Biofreeze gel. It is not fair to convert that prediction into proven superiority.

Menthol distinction: Biofreeze wins the concentration comparison. LactiGo competes on formulation differentiation, athlete-specific testing, and premium positioning—not on having the highest menthol number.

What Makes LactiGo a Premium Formula?

LactiGo's premium case is strongest when it is built on objective differentiation rather than exaggerated outcome claims.

1. A carnosine-magnesium formulation strategy

LactiGo's Drug Facts list L-carnosine and magnesium sulfate among its inactive ingredients.[1] That makes the formula meaningfully different from a conventional menthol-only story.

Carnosine is a naturally occurring dipeptide found in skeletal muscle and is involved in intracellular buffering and other biological functions. That background explains why athletes and researchers are interested in carnosine. It does not establish that applying a gel to skin increases carnosine inside human muscle. Carnosine also should not be confused with its dietary precursor; this guide explains the difference between beta-alanine and carnosine.

For a fuller explanation of exercise acidity, see why lactate is not simply the waste product behind the burn. That physiology does not prove a topical gel changes muscle pH.

Magnesium sulfate is also present in LactiGo's formula. The relevant U.S. patent describes a carnosine-magnesium complex and names magnesium sulfate as a suitable magnesium salt.[4] The current OTC label, however, classifies menthol—not carnosine or magnesium sulfate—as the active analgesic ingredient.[1]

2. Patent-protected formulation differentiation

U.S. Patent US10973868B2 is titled "Composition for topical use based on a carnosine-magnesium complex." Google Patents lists it as active, with Outplay Inc. as the current assignee.[4]

The patent's first claim covers a topical composition containing a specified amount of a carnosine-magnesium complex for delivering carnosine to skeletal muscle tissue. Additional claims cover topical forms and possible absorbing-enhancer components, including ethoxydiglycol—an ingredient also listed in LactiGo's current Drug Facts.[1,4]

That patent is a legitimate reason to describe LactiGo as technologically differentiated. A generic menthol comparison misses the point of what the premium buyer is purchasing.

3. Informed-Sport certification

LactiGo is listed as an Informed-Sport-certified brand. Informed-Sport states that certified products are tested for a broad range of substances prohibited in sport.[7]

For a competitive athlete subject to anti-doping rules, that quality-assurance layer can materially affect product choice. It reduces a specific contamination risk; it does not prove that LactiGo improves performance or relieves pain better.

4. Athlete-centered application experience

LactiGo describes its gel as fast-absorbing, quick-drying, and non-sticky. Those are manufacturer-reported experience attributes rather than clinical outcomes, but they matter in a pre-training, competition, or travel routine.[3]

Together, specialized formulation, patent protection, sport certification, and athlete-centered use create a coherent premium value proposition.

Why LactiGo earns the premium label: LactiGo is not merely a lower-menthol copy of Biofreeze. It is a specialized athlete-focused gel that combines label-supported menthol analgesia with a patented carnosine-magnesium formulation strategy and banned-substance testing. The premium is for differentiation and quality assurance—not a guarantee of superior pain relief.

What the LactiGo Patent Does—and Does Not—Prove

Patents are often misunderstood in supplement and topical-product marketing.

LactiGo's patent describes a carnosine-magnesium topical composition and laboratory skin-model testing; a patent is formulation evidence, not a head-to-head clinical verdict.

What the patent adds

US10973868B2 contains:

• claims covering a topical carnosine-magnesium composition;
• a reconstructed human epidermis experiment measuring carnosine in tissue homogenates and culture medium after 24 and 48 hours;
• a formulation example containing carnosine, magnesium sulfate, and an absorbing-enhancer component; and
• an 11-player soccer pilot comparing performance tests under different topical conditions.[4]

The epidermis experiment is relevant because it directly addresses a technical formulation challenge: carnosine is hydrophilic and skin is a substantial barrier. The patent reports differences in carnosine measurements in a laboratory-grown epidermis model.[4]

What the patent cannot establish by itself

A patent is a legal document that protects an invention meeting patentability requirements. It is not FDA approval, an independent systematic review, or automatic proof that a commercial product produces a clinically important outcome.

The reconstructed epidermis model is not a living human athlete and contains no skeletal muscle. The patent's soccer pilot was small, and the document does not supply the kind of large, independently replicated, blinded clinical program needed for broad superiority claims. The patent also does not compare LactiGo with Biofreeze.[4]

Patent distinction: The patent strengthens LactiGo's premium technology story and shows that the formulation is more than an ordinary menthol concept. It does not permit the claim that LactiGo is clinically proven to deliver carnosine into human muscle or outperform Biofreeze.

What Does the Human Evidence Show?

The fairest comparison looks at the available evidence for each product family and then acknowledges that the studies answer different questions.

LactiGo and topical-carnosine performance research

A 2025 triple-blind crossover study included seven world-class male rugby sevens players. Participants applied 10 mL of topical carnosine gel or placebo 40 minutes before 12 intermittent cycling sprints. Peak power was higher with the gel during Sprints 2, 4, and 7, but not every sprint. Mean power, heart rate, and perceived exertion did not show a treatment effect. The study did not measure carnosine in blood, interstitial fluid, or skeletal muscle.[5]

A 2023 randomized crossover trial in 15 trained male cyclists produced a conflicting result. A mentholated topical carnosine gel did not significantly improve the repeated Wingate performance outcomes measured in that study.[6]

These trials are interesting because they study performance rather than only cooling sensation. They are also too small and inconsistent to support a universal performance claim or establish a mechanism.

Biofreeze and pain-related research

Biofreeze has been used in several small musculoskeletal pain studies. A 20-person crossover study in knee osteoarthritis reported partial support for menthol gel, including reduced pain during several functional tasks, but between-treatment statistical findings and sample size limited the conclusion.[10]

A 36-person pilot study found that Biofreeze combined with chiropractic adjustments reduced acute low-back-pain measures more than chiropractic adjustments plus a control cream over four weeks. Because Biofreeze was combined with another intervention and the study was small, it does not isolate a universal Biofreeze effect.[11]

A 2017 review concluded that Biofreeze had produced clinically meaningful reductions in several populations while also emphasizing the lack of large, well-controlled trials. The paper listed its lead author with Performance Health, the company associated with Biofreeze at the time, so readers should also consider that industry affiliation when weighing the review.[13]

Why the evidence does not create a clean winner

LactiGo's distinctive research question is whether a topical carnosine formulation may affect athletic performance. Biofreeze's better-known studies mainly address pain or function. Those are different endpoints.

No direct randomized trial compares LactiGo and Biofreeze for:

• onset of cooling;
• magnitude or duration of pain relief;
• next-day soreness;
• repeated-sprint performance;
• skin tolerability; or
• user preference.

Evidence verdict: Biofreeze has more product-specific pain literature, although much of it is small and limited. LactiGo has a more distinctive athlete-performance research program, but the human findings are preliminary and mixed. Neither evidence base proves head-to-head superiority.

Feel, Formats, Availability, and Value

Clinical claims are not the only reasons people choose a topical product. Application experience can determine whether a product is actually used consistently.

Cooling intensity

Biofreeze's standard 4% gel will likely appeal to users who equate a pronounced cooling sensation with the experience they want. LactiGo's 1.25% menthol may appeal to users who prefer a less aggressive cooling profile while still using a label-directed topical analgesic. Individual experience will vary.[1,2]

Texture and routine

LactiGo markets its gel as fast-absorbing, quick-drying, and non-sticky. That athlete-centered experience fits warmups, training bags, and travel.[3]

Biofreeze offers hands-on gels, roll-ons for targeted mess-free use, sprays for hard-to-reach areas, patches for extended wear, and other formats. If applicator choice is the priority, Biofreeze has the clear advantage.[9]

Availability

Biofreeze has broad retail and clinician-channel familiarity. LactiGo is a more specialized purchase through its own sales channels and selected partners. The convenience advantage generally belongs to Biofreeze.

Price and premium value

At the time of research, LactiGo's official shop listed the 100 mL menthol gel at $55. Retail Biofreeze pricing varies by seller, format, and size and is generally lower. Prices can change; the live product page should be checked before purchase.[3,8]

The price question is therefore straightforward:

• If the buyer wants the lowest cost per ounce of conventional menthol relief, Biofreeze is likely the better value.
• If the buyer specifically values the patented carnosine-magnesium formulation strategy, Informed-Sport certification, and athlete-focused positioning, LactiGo provides the more complete premium proposition.

Paying more does not guarantee a stronger cooling sensation or superior analgesia. It buys a different formula, certification profile, and product philosophy.

Which Product Should You Choose?

Choose LactiGo if:

• you want a premium topical developed specifically around active lifestyles and sport;
• the patented carnosine-magnesium formulation is important to your purchasing decision;
• Informed-Sport certification matters because you compete under anti-doping rules;
• you prefer a lower-menthol gel rather than maximizing cooling intensity;
• a quick-drying, non-sticky application experience is important; or
• you accept that the topical-carnosine performance evidence is promising but preliminary and mixed.

Choose Biofreeze if:

• your main goal is a familiar, conventional menthol pain-relief experience;
• you prefer a standard gel with 4% menthol;
• you need a roll-on, spray, patch, cream, or other specialized applicator;
• broad retail availability matters;
• lower upfront cost is the priority; or
• you are not specifically seeking carnosine-magnesium formulation technology or sport certification.

Choose neither—and seek assessment—if:

• pain is sudden, severe, worsening, or associated with a pop;
• there is major swelling, deformity, weakness, numbness, loss of function, or inability to bear weight;
• symptoms follow a significant fall, collision, or other trauma;
• pain persists beyond label guidance or repeatedly returns;
• the skin is wounded, damaged, or significantly irritated; or
• temporary relief would tempt you to force activity through a possible injury.

Safety and Responsible Use

Read the Drug Facts on the exact container you own. Biofreeze formulas vary, and directions for gel, spray, cream, stick, and patch products are not interchangeable.

LactiGo label essentials

LactiGo is for external use only. Avoid the eyes and mucous membranes. Do not apply it to wounds or damaged skin, and do not bandage the area tightly. Adults and children two years and older may apply it to the affected area no more than three to four times daily; consult a doctor for children under two. Stop use and consult a doctor if the condition worsens, persists beyond seven days, or clears and returns within a few days.[1]

Standard Biofreeze gel label essentials

The standard Biofreeze gel is for external use only and is flammable. Avoid eyes and mucous membranes, damaged or irritated skin, tight bandaging, and heating pads or devices. The label directs adults and children two and older to rub a thin film over the affected area no more than three to four times daily and wash hands with cool water after use. Consult the label and a professional for the listed stop-use, pregnancy, breastfeeding, and child-use cautions.[2]

Do not layer the products

Do not apply LactiGo and Biofreeze to the same area at the same time. Combining topical analgesics can increase irritation and makes it difficult to identify which product caused a reaction. The Biofreeze label specifically cautions against use with other ointments, creams, sprays, or liniments in some current formulations.[2]

Temporary comfort is not evidence that injured tissue is ready for more load. Ordinary delayed-onset muscle soreness and an acute injury are also not the same problem; severe, focal, or worsening pain deserves assessment.

Final Verdict: LactiGo Is the Premium Formula; Biofreeze Is the Conventional Value Choice

LactiGo deserves to be considered a premium solution. Its value proposition is not that 1.25% menthol somehow "beats" 4% menthol. It is that LactiGo pairs its label-supported topical-analgesic role with a specialized athlete-focused formula, an active patent covering carnosine-magnesium topical technology, Informed-Sport certification, and an application experience designed for active routines.[1,3,4,7]

Biofreeze remains a credible and practical choice. It offers a higher-menthol standard gel, broad availability, many formats, and a lower typical price. For someone seeking only familiar cooling pain relief, those advantages may matter more.[2,8,9]

For the athlete who asks, "Which product offers the more differentiated formulation and premium sport-specific proposition?" the answer is LactiGo.

For the shopper who asks, "Which product is easier to find, less expensive, and available in the most formats?" the answer is Biofreeze.

For the question, "Which product is clinically proven to provide better pain relief in a direct comparison?" the honest answer is neither—because that head-to-head trial has not been done.

That transparency is not a weakness. It is the reason an informed reader can trust the recommendation.

Medical and editorial disclaimer: This article is for educational purposes and does not diagnose or treat an injury or medical condition. Follow the Drug Facts on the exact product you use. Seek professional care for severe, worsening, traumatic, recurrent, or persistent pain and for any loss of function, major swelling, numbness, weakness, or deformity.

Frequently Asked Questions

Is LactiGo better than Biofreeze?

LactiGo is the better premium choice for an athlete who values its patented carnosine-magnesium formulation strategy and Informed-Sport certification. Biofreeze is the better conventional choice for higher-menthol cooling, more formats, broad availability, and lower typical cost. No direct clinical trial proves that either finished product provides better pain relief.

What is the main difference between LactiGo and Biofreeze?

Both are menthol topical analgesics, but their formulas and positioning differ. LactiGo contains menthol 1.25% and lists L-carnosine and magnesium sulfate as inactive ingredients. The standard Biofreeze Pain Relief Gel contains menthol 4% and uses a different formula with botanical extracts, camphor, alcohol, and other inactive ingredients.

Does Biofreeze work better because it has more menthol?

Not necessarily. The standard Biofreeze gel has a higher menthol percentage and may feel more intensely cooling, but concentration alone does not prove that the complete product provides better or longer pain relief. Vehicle, dose, skin area, other ingredients, and individual sensitivity also matter.

What makes LactiGo a premium product?

LactiGo combines label-supported menthol analgesia with an athlete-focused formula containing L-carnosine and magnesium sulfate, an active U.S. patent covering a topical carnosine-magnesium complex, Informed-Sport certification, and a manufacturer-described quick-drying, non-sticky application experience.

Does LactiGo's patent prove that carnosine reaches human muscle?

No. The patent includes claims and experiments involving a reconstructed human epidermis model plus a small athlete pilot, but it does not provide independent confirmation that commercial LactiGo raises carnosine inside living human skeletal muscle. A patent is intellectual-property protection, not FDA approval or a clinical superiority finding.

Is LactiGo clinically proven to improve athletic performance?

The human evidence is preliminary and mixed. A 2025 seven-player rugby study reported higher peak power during selected sprints, while a 2023 trial in 15 trained cyclists found no performance improvement. Larger independent studies that measure tissue delivery and prespecify outcomes are needed.

Is LactiGo Informed-Sport certified?

Yes. LactiGo is listed as an Informed-Sport-certified brand. That certification concerns testing for substances prohibited in sport. It is valuable quality assurance for tested athletes, but it does not prove that the product improves performance or relieves pain better.

Can I use LactiGo and Biofreeze together?

Do not layer LactiGo and Biofreeze on the same area. Combining topical analgesics may increase skin irritation and can make it difficult to identify the cause of a reaction. Follow the Drug Facts for one product at a time and ask a healthcare professional if you are unsure.

Which product offers more application formats?

Biofreeze. Its product range includes gels, roll-ons, sprays, patches, creams, sticks, and other variants. LactiGo's advantage is specialized athlete-focused formulation rather than the widest selection of applicators.

Which product is the better value?

Biofreeze is generally the lower-cost choice for conventional menthol relief. LactiGo is the premium-value choice for a buyer who specifically wants the patented carnosine-magnesium formulation strategy, Informed-Sport certification, and athlete-centered product experience.

External References

1. DailyMed. "Label: LACTIGO—menthol gel." U.S. National Library of Medicine. Updated September 3, 2024. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=849c3601-2bc8-0991-e053-2a91aa0a5e7f
2. DailyMed. "Label: BIOFREEZE—menthol gel." Reckitt Benckiser LLC. Updated May 13, 2026. Menthol USP 4% standard gel label. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=83d5c2f2-2413-4d28-83b2-0808d0917b4d
3. LactiGo. "LactiGo Performance and Recovery Gel with Menthol [100 mL]" and "The Science Behind LactiGo." Product and science pages accessed August 4, 2026. https://shop.lactigo.com/product/lactigo-performance-and-recovery-gel-with-menthol-100ml/01tan000009uATSAA2 and https://shop.lactigo.com/the-science
4. Macias C, Sharpe T, Ferrari M, inventors; Outplay Inc., assignee. "Composition for topical use based on a carnosine-magnesium complex." U.S. Patent 10,973,868 B2. Issued April 13, 2021. https://patents.google.com/patent/US10973868B2/en
5. Beaven CM, James C, McMaster DT, Brockelbank N. "Topical carnosine gel improves intermittent high-intensity exercise performance in world-class rugby sevens players." Journal of the International Society of Sports Nutrition. 2025;22(1):2550311. doi:10.1080/15502783.2025.2550311. https://pubmed.ncbi.nlm.nih.gov/40859880/
6. Harnish CR, Miller B. "Transdermal carnosine gel fails to improve repeated Wingate performance in trained male cyclists: A randomized controlled cross-over trial." Journal of Sports Science and Nutrition. 2023;4(2):106–111. doi:10.33545/27077012.2023.v4.i2b.193. https://doi.org/10.33545/27077012.2023.v4.i2b.193
7. Informed Sport. "Certified Product Brands: LactiGo." Accessed August 4, 2026. https://www.informed-sport.com/certified-product-brands
8. Biofreeze. "Biofreeze Pain Relief Gel, 3 fl oz. Tube, Green." Product page accessed August 4, 2026. https://biofreeze.com/products/biofreeze-pain-relief-gel-tube/
9. Biofreeze. "Our Products." Product formats page accessed August 4, 2026. https://biofreeze.com/products/
10. Topp R, Brosky JA Jr, Pieschel D. "The effect of either topical menthol or a placebo on functioning and knee pain among patients with knee OA." Journal of Geriatric Physical Therapy. 2013;36(2):92–99. doi:10.1519/JPT.0b013e318268dde1. https://pubmed.ncbi.nlm.nih.gov/22976810/
11. Zhang J, Enix D, Snyder B, Giggey K, Tepe R. "Effects of Biofreeze and chiropractic adjustments on acute low back pain: a pilot study." Journal of Chiropractic Medicine. 2008;7(2):59–65. doi:10.1016/j.jcme.2008.02.004. https://pubmed.ncbi.nlm.nih.gov/19674721/
12. Li Z, Zhang H, Wang Y, Li Y, Li Q, Zhang L. "The distinctive role of menthol in pain and analgesia: mechanisms, practices, and advances." Frontiers in Molecular Neuroscience. 2022;15:1006908. doi:10.3389/fnmol.2022.1006908. https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2022.1006908/full
13. Page P, Alexander L. "The clinical effectiveness of Biofreeze topical analgesic on musculoskeletal pain: a systematic review." Journal of Performance Health Research. 2017;1(1):1–10. doi:10.25036/jphr.2017.1.1.page. https://www.researchgate.net/publication/317595130_The_Clinical_Effectiveness_of_Biofreeze_R_Topical_Analgesic_on_Musculoskeletal_Pain_A_Systematic_Review

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